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Disease Management Clinical Decisions

When Fevers May Not Be a Sign of Infection


Release Date:   October 3, 2012

Estimated Time of Completion:  15 minutes


Each lesson within the Disease Management Clinical Decisions series includes an optional related reading material from The Cleveland Clinic Disease Management Project or the Cleveland Clinic Journal of Medicine, an interactive case, and an evaluation.

Throughout the interactive case-based lesson, you may proceed to the next question once you answer each question correctly. In addition to allowing you to proceed, the correct answer also reveals the rationale for the answer.

Upon completing the CME activity, the evaluation and registration forms, you will have an opportunity to print your CME certificate for your records.

Learning Objectives

At the conclusion of this activity, the participant will be able to:

  1. Recognize autoinflamamtory diseases result from genetically mediated defects of the immune system that cause recurrent episodes of fevers, rashes, serositis, and musculoskeletal inflammation.
  2. Discuss the diagnostic evaluation of suspected autoinflammatory syndromes that result in recurrent fevers.
  3. Review treatment options for patients with autoinflammatory syndromes.

Target Audience

Directed to primary care physicians including family practitioners and internists.

Activity Director and Faculty

Activity Director

Kenneth Goodman, MD
Department of Family Medicine
Associate Director, Research and Development - Center for Continuing Medical Education
Cleveland Clinic
Cleveland, Ohio


Steven Spalding, MD
Director, Center for Pediatric Rheumatology
Center for Vasculitis Care & Research
Department of Rheumatologic & Immunologic Disease
Business Intelligence, Medical Operations
Cleveland Clinic
Cleveland, Ohio


The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician or other health care provider relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this educational activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation or Peking Union Medical College Hospital be liable for any decision made or action taken in reliance upon the information provided through this educational activity.


In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Foundation Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty have indicated that they have no relationship which, in the context of their presentations, could be perceived as a potential conflict of interest:

Kenneth Goodman, MD
Steven Spalding, MD

Begin Activity in English

How to Obtain Your Certificate of Participation

  1. Participate in the activity.
  2. Login to your account.
  3. Complete the evaluation.
  4. Print your certificate.