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Case-Based Lessons from the Cleveland Clinic Journal of Medicine:
Treating and Preventing Acute Gout Attacks

Acute Polyarthritis


Release Date:   June 4, 2010

Estimated Time of Completion:  15 minutes


This is an interactive case-based lesson from the Cleveland Clinic Journal of Medicine. Read each section of the case and answer the questions. You may proceed to the next section once you answer each question correctly. In addition to allowing you to proceed, the correct answer also reveals the rationale, with references when appropriate. Upon completing the CME activity and the evaluation and registration forms, you will have an opportunity to print your CME certificate for your records.


The purpose of this case-based lesson is to narrow practice and knowledge gaps in the diagnosis and management of acute polyarticular arthritis.

Learning Objectives

At the conclusion of this activity, the participant will be able to:

  1. Recognize gout as a cause of acute polyarthritis.

  2. Identify appropriate treatment options for polyarticular gout attacks.

Target Audience

This activity is directed to internists, family and general practitioners, rheumatologists, hospitalists, emergency physicians, and other physicians who manage patients with or at risk for gout attacks.

Activity Director and Faculty

Activity Director

Brian F. Mandell, MD, PhD
Professor and Chairman of Medicine, Education Institute,
and Department of Rheumatic and Immunologic Diseases,
Center for Vasculitis Care and Research,
Cleveland Clinic
Cleveland, OH


Alexandra Villa-Forte, MD, MPH
Department of Rheumatic and Immunologic Diseases,
Cleveland Clinic, Cleveland, OH


The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician or other health care provider relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this educational activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation or Peking Union Medical College Hospital be liable for any decision made or action taken in reliance upon the information provided through this educational activity.


In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Foundation Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty has indicated that he may have a relationship which, in the context of his presentation, could be perceived as a potential conflict of interest:

Brian F. Mandell, MD, PhD
Consulting URL Pharma (one-time consultation), Takeda Pharmaceuticals
Teaching and Speaking Takeda Pharmaceuticals (in a funded CME program)

The following faculty has indicated that she has no relationship which, in the context of her presentation, could be perceived as potential conflict of interest:

Alexandra Villa-Forte, MD, MPH

All other planners, CME staff, and content reviewers have no relevant financial relationships to disclose.

Begin Activity in English

How to Obtain Your Certificate of Participation

  1. Participate in the activity.
  2. Login to your account.
  3. Complete the evaluation.
  4. Print your certificate.